BIOACTIVE INVESTIGATION AND STRUCTURAL ELUCIDATION OF IRON (III) AND NICOTINOHYDROXAMIC ACID COMPLEX
Keywords:
Mix bonding mode, microorganism and octahedral coordinationAbstract
Complex of Fe (III) with nicotinohydroxamic acid (NHA) has been investigated by using spectrophotometric method. Fe (III) in aqueous solution revealed the sole formation of the 1:3 complexes at equilibrium. The spectra and magnetic studies of the isolated complex indicated octahedral coordination. The bonding mode proposed for the Fe (III) hydroxamate complex is mix bonding mode (N,O). The complex is biologically active against the eight (8) microorganism investigated. The ligand and its complex showed moderate activity at 50 µg/ml against the microbes while at 200 µg/ml both the ligand and its complex showed maximum activity.
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