BIOACTIVE INVESTIGATION AND STRUCTURAL ELUCIDATION OF IRON (III) AND NICOTINOHYDROXAMIC ACID COMPLEX

Authors

  • Aliyu A.O. Department of Chemistry, Nigerian Defence Academy, PMB 2109, Kaduna.
  • Nwabueze J.N. Department of Chemistry, University of Abuja, PMB 117, FCT, Abuja, Nigeria.

Keywords:

Mix bonding mode, microorganism and octahedral coordination

Abstract

Complex of Fe (III) with nicotinohydroxamic acid (NHA) has been investigated by using spectrophotometric method. Fe (III) in aqueous solution revealed the sole formation of the 1:3 complexes at equilibrium. The spectra and magnetic studies of the isolated complex indicated octahedral coordination. The bonding mode proposed for the Fe (III) hydroxamate complex is mix bonding mode (N,O). The complex is biologically active against the eight (8) microorganism investigated. The ligand and its complex showed moderate activity at 50 µg/ml against the microbes while at 200 µg/ml both the ligand and its complex showed maximum activity.

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Published

2008-12-01

How to Cite

Aliyu A.O., & Nwabueze J.N. (2008). BIOACTIVE INVESTIGATION AND STRUCTURAL ELUCIDATION OF IRON (III) AND NICOTINOHYDROXAMIC ACID COMPLEX. Academy Journal of Science and Engineering, 5(1), 30–38. Retrieved from https://ajse.academyjsekad.edu.ng/index.php/new-ajse/article/view/157